Automatic dissociation between microvasculature and larger vessels for ultrasound contrast imaging

Antonios Perperidis, David Thomas, Michalakis Averkiou, Colin Duncan, Alan McNeilly, Mairead Butler, Vassilis Sboros

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Citations (Scopus)

Abstract

Microvasculature density (MVD) provides an established biomarker for the prognosis of numerous diseases associated with abnormal microvascular networks. The accurate, robust and timely assessment of MVD changes facilitates disease detection, treatment monitoring and patient stratification. Nevertheless, the current gold standard (PET) for MVD quantification is not used in clinical practice due to its high costs and potential health hazards. Contrast Enhanced Ultrasound (CEUS) imaging can provide an attractive alternative. However, the limited dissociation between larger vessels and microvasculature in the imaged tissues limits the accuracy and robustness of CEUS. This study proposed a novel, and fully automatic technique that dissociates larger vessels from microvasculature in CEUS imaged tissues. The ovine Corpus Luteum (CL) was used as an in vivo model for the development and assessment of the proposed technique.

Original languageEnglish
Title of host publication2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
Place of PublicationNew York
PublisherIEEE
Pages5076-5079
Number of pages4
DOIs
Publication statusPublished - 2014
Event36th Annual International Conference of the IEEE-Engineering-in-Medicine-and-Biology-Society - Chicago, Israel
Duration: 26 Aug 201430 Aug 2014

Publication series

NameIEEE Engineering in Medicine and Biology Society Conference Proceedings
PublisherIEEE
ISSN (Print)1557-170X

Conference

Conference36th Annual International Conference of the IEEE-Engineering-in-Medicine-and-Biology-Society
Abbreviated titleEMBC
CountryIsrael
Period26/08/1430/08/14

Keywords

  • CORPUS-LUTEUM
  • QUANTIFICATION
  • ECHOCARDIOGRAPHY
  • PERFUSION
  • AGENTS

Cite this

Perperidis, A., Thomas, D., Averkiou, M., Duncan, C., McNeilly, A., Butler, M., & Sboros, V. (2014). Automatic dissociation between microvasculature and larger vessels for ultrasound contrast imaging. In 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) (pp. 5076-5079). (IEEE Engineering in Medicine and Biology Society Conference Proceedings). IEEE. https://doi.org/10.1109/EMBC.2014.6944766