This paper presents an optimisation-based, automated procedure known as automated targeting to analyse a total property-based network that consists of the individual elements of material reuse/recycle, regeneration/interception and waste treatment. Due to the close interaction among these individual elements, simultaneous synthesis of a total network is considered. This optimisation-based approach provides the same benefits as conventional pinch analysis techniques, in yielding various network targets prior to detailed design. Besides, the flexibility in setting objective function is the major advantage of the automated targeting approach over the conventional targeting techniques. An industrial example is utilised for illustration.