Application of Proteomics to Elucidate Bacterium-Host Interactions

David George Emslie Smith*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

Original languageEnglish
Title of host publicationMethods in Animal Proteomics
Number of pages30
ISBN (Electronic)9780470960660
ISBN (Print)9780813817910
Publication statusPublished - 2011


  • Application of proteomics - elucidating bacterium-host interactions
  • Applications of proteomics techniques - to bacterial pathogens, varied
  • Immunoproteomics - bacterial pathogens and host interaction, and immune response
  • Outcome validation - using extended panel of isolates, combined with proteomics, molecular, immunochemical or other approach
  • Pathogen-host interaction in vivo - practical challenges, and infection system suitability
  • Pathogenic insult, and cell and tissue alteration - pathogen and host integration, and "omics"
  • Proteomics analyses, of bacterial protein content - in whole cell preparations
  • Stages, bacterial infection of host animal - response to alterations in environmental signals
  • Surrogate conditions, bacterial (sub)proteome surveys - isolates, cultured in laboratories under "ideal" conditions
  • Zoonotic bacteria, crossing between host species - and disease in hosts

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)

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