API-centric linked data integration: the Open PHACTS discovery platform case study

Paul Groth*, Antonis Loizou, Alasdair J G Gray, Carole Goble, Lee Harland, Steve Pettifer

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

54 Citations (Scopus)


Data integration is a key challenge faced in pharmacology where there are numerous heterogeneous databases spanning multiple domains (e.g. chemistry and biology). To address this challenge, the Open PHACTS consortium has developed the Open PHACTS Discovery Platform that leverages Linked Data to provide integrated access to pharmacology databases. Between its launch in April 2013 and March 2014, the platform has been accessed over 13.5 million times and has multiple applications that integrate with it. In this work, we discuss how Application Programming Interfaces can extend the classical Linked Data Application Architecture to facilitate data integration. Additionally, we show how the Open PHACTS Discovery Platform implements this extended architecture.

Original languageEnglish
Pages (from-to)12-18
Number of pages7
JournalJournal of Biomedical Semantics
Publication statusPublished - Dec 2014


  • API
  • Data integration
  • Data spaces
  • Linked Data
  • Pharmacology


Dive into the research topics of 'API-centric linked data integration: the Open PHACTS discovery platform case study'. Together they form a unique fingerprint.

Cite this