An extract from teak (Tectona grandis) bark inhibited Listeria monocytogenes and methicillin resistant Staphylococcus aureus

A. Neamatallah, L. Yan, S. J. Dewar, B. Austin

    Research output: Contribution to journalArticle

    23 Citations (Scopus)

    Abstract

    Aims: The aim of this study was to characterize the inhibitory mechanism in teak (Tectona grandis) bark and to determine its effectiveness against Listeria monocytogenes and methicillin resistant Staphylococcus aureus (MRSA). Methods and Results: Methanol extracts of teak bark were inhibitory to L. monocytogenes and MRSA by means of disc diffusion. Gas chromatography-mass spectrometry, and 1H and 3C nuclear mass resonance analyses revealed that the inhibitory compound had a molecular weight of 174, and a structure of 5-hydroxy-1,4-naphthalenedione (Juglone). Conclusions: 5-hydroxy-1,4- naphthalenedione (Juglone) inhibited L. monocytogenes and MRSA. Significance and Impact of the Study: A compound in an extract of teak bark was inhibitory to L. monocytogenes and MRSA. © 2005 The Society for Applied Microbiology.

    Original languageEnglish
    Pages (from-to)94-96
    Number of pages3
    JournalLetters in Applied Microbiology
    Volume41
    Issue number1
    DOIs
    Publication statusPublished - 2005

    Keywords

    • 5-hydroxy-1,4-naphthalenedione
    • Antibacterial activity
    • Juglone
    • Listeria monocytogenes
    • Staphylococcus aureus
    • Teak (Tectona grandis)

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