The rate of fermentation of both d-glucose and maltose in a defined medium by a brewing strain of Saccharomyces cerevisiae was found to be dependent on the availability of NH4+. The glycolytic rate did not correlate with intracellular NH4+ and activation by NH4+ was blocked by cycloheximide. The ability of several amino acids to activate glycolysis followed the same order as their effectiveness as sole sources of nitrogen. It therefore seems that NH4+ does not stimulate fermentation through direct activation of glycolytic enzymes, but through its function as a substrate for protein synthesis. © 1984.
|Number of pages||4|
|Journal||Enzyme and Microbial Technology|
|Publication status||Published - Aug 1984|
- ammonium ion
- Saccharomyces cerevisiae