Abstract
A new total synthesis of (-)-suaveoline from L-tryptophan is reported (overall yield ca. 14%); key steps include a high yielding cis-specific Pictet-Spengler reaction, a one-pot Horner-Wadsworth-Emmons/alkylation procedure, a vinylogous Thorpe cyclization and the direct formation of a pyridine from a 1,5-dinitrile.
| Original language | English |
|---|---|
| Pages (from-to) | 1479-1480 |
| Number of pages | 2 |
| Journal | Chemical Communications |
| Issue number | 12 |
| Publication status | Published - 1996 |