A total asymmetric synthesis of (-)-suaveoline

Patrick D. Bailey, Keith M. Morgan

Research output: Contribution to journalArticle

Abstract

A new total synthesis of (-)-suaveoline from L-tryptophan is reported (overall yield ca. 14%); key steps include a high yielding cis-specific Pictet-Spengler reaction, a one-pot Horner-Wadsworth-Emmons/alkylation procedure, a vinylogous Thorpe cyclization and the direct formation of a pyridine from a 1,5-dinitrile.

Original languageEnglish
Pages (from-to)1479-1480
Number of pages2
JournalChemical Communications
Issue number12
Publication statusPublished - 1996

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Cyclization
Alkylation
Tryptophan
pyridine

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Bailey, P. D., & Morgan, K. M. (1996). A total asymmetric synthesis of (-)-suaveoline. Chemical Communications, (12), 1479-1480.
Bailey, Patrick D. ; Morgan, Keith M. / A total asymmetric synthesis of (-)-suaveoline. In: Chemical Communications. 1996 ; No. 12. pp. 1479-1480.
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Bailey, PD & Morgan, KM 1996, 'A total asymmetric synthesis of (-)-suaveoline', Chemical Communications, no. 12, pp. 1479-1480.

A total asymmetric synthesis of (-)-suaveoline. / Bailey, Patrick D.; Morgan, Keith M.

In: Chemical Communications, No. 12, 1996, p. 1479-1480.

Research output: Contribution to journalArticle

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AU - Morgan, Keith M.

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Bailey PD, Morgan KM. A total asymmetric synthesis of (-)-suaveoline. Chemical Communications. 1996;(12):1479-1480.