Abstract
A new total synthesis of (-)-suaveoline from L-tryptophan is reported (overall yield ca. 14%); key steps include a high yielding cis-specific Pictet-Spengler reaction, a one-pot Horner-Wadsworth-Emmons/alkylation procedure, a vinylogous Thorpe cyclization and the direct formation of a pyridine from a 1,5-dinitrile.
Original language | English |
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Pages (from-to) | 1479-1480 |
Number of pages | 2 |
Journal | Chemical Communications |
Issue number | 12 |
Publication status | Published - 1996 |