A new synthesis of formycin via nitropyrazole derivatives

J. Grant Buchanan; Alan R. Edgar; Roderick J. Hutchison; Alan Stobie; Richard H. Wightman

A new synthesis of formycin via nitropyrazole derivatives

J. Grant Buchanan
, Alan R. Edgar
, Roderick J. Hutchison
, Alan Stobie
, Richard H. Wightman

School of Engineering & Physical Sciences

Research output: Contribution to journal › Article › peer-review

42 Citations (Scopus)

Abstract

3-(2,3,5-Tri-O-benzyl-ß-D-ribofuranosyl)pyrazole (4) has been converted into formycin (15) by a sequence involving, as the key step, cine substitution, by cyanide ion, of the l-nitro group in the 1,4-dinitropyrazole (10).

Original language	English
Pages (from-to)	237-238
Number of pages	2
Journal	Journal of the Chemical Society, Chemical Communications
Issue number	5
Publication status	Published - 1980

Cite this

@article{9bb06f531edb4df1baf7272b34453d0f,

title = "A new synthesis of formycin via nitropyrazole derivatives",

abstract = "3-(2,3,5-Tri-O-benzyl-{\ss}-D-ribofuranosyl)pyrazole (4) has been converted into formycin (15) by a sequence involving, as the key step, cine substitution, by cyanide ion, of the l-nitro group in the 1,4-dinitropyrazole (10).",

author = "Buchanan, \{J. Grant\} and Edgar, \{Alan R.\} and Hutchison, \{Roderick J.\} and Alan Stobie and Wightman, \{Richard H.\}",

year = "1980",

language = "English",

pages = "237--238",

journal = "Journal of the Chemical Society, Chemical Communications",

issn = "0022-4936",

publisher = "Chemical Society",

number = "5",

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TY - JOUR

T1 - A new synthesis of formycin via nitropyrazole derivatives

AU - Buchanan, J. Grant

AU - Edgar, Alan R.

AU - Hutchison, Roderick J.

AU - Stobie, Alan

AU - Wightman, Richard H.

PY - 1980

Y1 - 1980

N2 - 3-(2,3,5-Tri-O-benzyl-ß-D-ribofuranosyl)pyrazole (4) has been converted into formycin (15) by a sequence involving, as the key step, cine substitution, by cyanide ion, of the l-nitro group in the 1,4-dinitropyrazole (10).

AB - 3-(2,3,5-Tri-O-benzyl-ß-D-ribofuranosyl)pyrazole (4) has been converted into formycin (15) by a sequence involving, as the key step, cine substitution, by cyanide ion, of the l-nitro group in the 1,4-dinitropyrazole (10).

UR - https://www.scopus.com/pages/publications/0005931496

M3 - Article

SN - 0022-4936

SP - 237

EP - 238

JO - Journal of the Chemical Society, Chemical Communications

JF - Journal of the Chemical Society, Chemical Communications

IS - 5

ER -

A new synthesis of formycin via nitropyrazole derivatives

Abstract

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