A new synthesis of formycin via nitropyrazole derivatives

J. Grant Buchanan, Alan R. Edgar, Roderick J. Hutchison, Alan Stobie, Richard H. Wightman

Research output: Contribution to journalArticlepeer-review

40 Citations (Scopus)


3-(2,3,5-Tri-O-benzyl-ß-D-ribofuranosyl)pyrazole (4) has been converted into formycin (15) by a sequence involving, as the key step, cine substitution, by cyanide ion, of the l-nitro group in the 1,4-dinitropyrazole (10).

Original languageEnglish
Pages (from-to)237-238
Number of pages2
JournalJournal of the Chemical Society, Chemical Communications
Issue number5
Publication statusPublished - 1980


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