TY - JOUR
T1 - A Methodology for Remote Microwave Sterilization Applicable to the Coronavirus and Other Pathogens using Retrodirective Antenna Arrays
AU - Kossenas, Konstantinos
AU - Podilchak, Symon K.
AU - Comite, Davide
AU - Hilario Re, Pascual D.
AU - Goussetis, George
AU - Pavuluri, Sumanth Kumar
AU - Griffiths, Samantha
AU - Chadwick, Robert
AU - Guo, Chao
AU - Bruns, Nico
AU - Burkard, Christine
AU - Haas, Juergen
AU - Desmulliez, Marc
N1 - Funding Information:
This work was supported in part by Engineering & Physical Research Science (EPSRC) funding agency through the platform grant “Multi-Modal Manufacturing of Medical Devices (4mD)” under Grant EP/P027415/1, in part by the Biotechnology and Biological Sciences Research Council Institute Strategic Program grant funding The Roslin Institute under Grants BBS/E/D/20241866, BBS/E/D/20002172, and BBS/E/D/20002174. The work of Jürgen G. Haas was supported by Grants BBSRC BB/T003138/1, MRC MR/P011349/1 and IMI2 CARE.
Publisher Copyright:
© 2016 IEEE.
PY - 2022/3
Y1 - 2022/3
N2 - This paper describes an innovative remote surface sterilization approach applicable to the new coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The process is based on the application of a liquid film on the surface or object under sterilization (OUS). A beacon signal is used to self-steer the transmitted power from the designed retrodirective antenna array (RDA) towards the OUS using circularly polarized fields; then, the sterilization is completed by raising and maintaining the required temperature for a certain time. Results suggest that the process takes 5 minutes or less for an angular coverage range over 60 degrees whilst abiding by the relevant safety protocols. This paper also models the power incident onto the OUS, providing consistent results with full-wave simulations. A practical RDA system is developed using a 2 × 1 microstrip patch array operating at 2.5 GHz and tested through the positioning of a representative target surface. Measurements, developed by sampling the power transmitted by the heterodyne RDA, are reported for various distances and angles, operating in the near-field of the system. To further validate the methodology, an additional experiment investigating virus deactivation through microwave heating was also developed. Measurements have been performed with an open cavity microwave oven on the Coronavirus (strain 229E) and egg white protein in a cuvette. This demonstrates that the temperature increases of aqueous films up to 70 $^{\circ }$C by remote microwave-induced heat can denature proteins and deactivate viruses. Possible applications of the method include sterilization of ambulances, medical equipment, and internet of things (IoT) devices.
AB - This paper describes an innovative remote surface sterilization approach applicable to the new coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The process is based on the application of a liquid film on the surface or object under sterilization (OUS). A beacon signal is used to self-steer the transmitted power from the designed retrodirective antenna array (RDA) towards the OUS using circularly polarized fields; then, the sterilization is completed by raising and maintaining the required temperature for a certain time. Results suggest that the process takes 5 minutes or less for an angular coverage range over 60 degrees whilst abiding by the relevant safety protocols. This paper also models the power incident onto the OUS, providing consistent results with full-wave simulations. A practical RDA system is developed using a 2 × 1 microstrip patch array operating at 2.5 GHz and tested through the positioning of a representative target surface. Measurements, developed by sampling the power transmitted by the heterodyne RDA, are reported for various distances and angles, operating in the near-field of the system. To further validate the methodology, an additional experiment investigating virus deactivation through microwave heating was also developed. Measurements have been performed with an open cavity microwave oven on the Coronavirus (strain 229E) and egg white protein in a cuvette. This demonstrates that the temperature increases of aqueous films up to 70 $^{\circ }$C by remote microwave-induced heat can denature proteins and deactivate viruses. Possible applications of the method include sterilization of ambulances, medical equipment, and internet of things (IoT) devices.
KW - COVID-19
KW - SARS-CoV-2
KW - medical devices
KW - microwave heating
KW - near field
KW - remote sterilization
KW - retrodirective array
UR - http://www.scopus.com/inward/record.url?scp=85105861196&partnerID=8YFLogxK
U2 - 10.1109/JERM.2021.3077110
DO - 10.1109/JERM.2021.3077110
M3 - Article
C2 - 35582462
AN - SCOPUS:85105861196
SN - 2469-7257
VL - 6
SP - 41
EP - 51
JO - IEEE Journal of Electromagnetics, RF and Microwaves in Medicine and Biology
JF - IEEE Journal of Electromagnetics, RF and Microwaves in Medicine and Biology
IS - 1
ER -