A femtosecond laser inscribed biochip for stem cell therapeutic applications

D. Choudhury; W. T. Ramsay; G. Brown; N. D. Psaila; S. Beecher; R. R. Thomson; R. Kiss; S. Pells; N. A. Willoughby; L. Paterson; A. K. Kar

doi:10.1117/12.874954

A femtosecond laser inscribed biochip for stem cell therapeutic applications

D. Choudhury, W. T. Ramsay, G. Brown, N. D. Psaila, S. Beecher, R. R. Thomson, R. Kiss, S. Pells, N. A. Willoughby, L. Paterson, A. K. Kar

School of Engineering & Physical Sciences

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

A continuous flow microfluidic cell separation platform has been designed and fabricated using femtosecond laser inscription. The device is a scalable and non-invasive cell separation mechanism aimed at separating human embryonic stem cells from differentiated cells based on the dissimilarities in their cytoskeletal elasticity. Successful demonstration of the device has been achieved using human leukemia cells the elasticity of which is similar to that of human embryonic stem cells. © 2011 Copyright Society of Photo-Optical Instrumentation Engineers (SPIE).

Original language	English
Title of host publication	Microfluidics, BioMEMS, and Medical Microsystems IX
Editors	H Becker, BL Gray
Place of Publication	BELLINGHAM
Publisher	SPIE
Pages	-
Number of pages	6
Volume	7929
ISBN (Print)	9780819484666
DOIs	https://doi.org/10.1117/12.874954
Publication status	Published - 2011
Event	Conference on Microfluidics, BioMEMS, and Medical Microsystems IX - San Francisco Duration: 23 Jan 2011 → 25 Jan 2011

Conference

Conference	Conference on Microfluidics, BioMEMS, and Medical Microsystems IX
City	San Francisco
Period	23/01/11 → 25/01/11

Keywords

cell separation
cell sorting
chemical etching
femtosecond laser inscription
fused silica
human embryonic stem cells

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10.1117/12.874954

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Choudhury, D., Ramsay, W. T., Brown, G., Psaila, N. D., Beecher, S., Thomson, R. R., Kiss, R., Pells, S., Willoughby, N. A., Paterson, L., & Kar, A. K. (2011). A femtosecond laser inscribed biochip for stem cell therapeutic applications. In H. Becker, & BL. Gray (Eds.), Microfluidics, BioMEMS, and Medical Microsystems IX (Vol. 7929, pp. -). SPIE. https://doi.org/10.1117/12.874954

@inproceedings{1c21a2e47989457d8bbd98012995aa61,

title = "A femtosecond laser inscribed biochip for stem cell therapeutic applications",

abstract = "A continuous flow microfluidic cell separation platform has been designed and fabricated using femtosecond laser inscription. The device is a scalable and non-invasive cell separation mechanism aimed at separating human embryonic stem cells from differentiated cells based on the dissimilarities in their cytoskeletal elasticity. Successful demonstration of the device has been achieved using human leukemia cells the elasticity of which is similar to that of human embryonic stem cells. {\textcopyright} 2011 Copyright Society of Photo-Optical Instrumentation Engineers (SPIE).",

keywords = "cell separation, cell sorting, chemical etching, femtosecond laser inscription, fused silica, human embryonic stem cells",

author = "D. Choudhury and Ramsay, {W. T.} and G. Brown and Psaila, {N. D.} and S. Beecher and Thomson, {R. R.} and R. Kiss and S. Pells and Willoughby, {N. A.} and L. Paterson and Kar, {A. K.}",

year = "2011",

doi = "10.1117/12.874954",

language = "English",

isbn = "9780819484666",

volume = "7929",

pages = "--",

editor = "H Becker and BL Gray",

booktitle = "Microfluidics, BioMEMS, and Medical Microsystems IX",

publisher = "SPIE",

address = "United States",

note = "Conference on Microfluidics, BioMEMS, and Medical Microsystems IX ; Conference date: 23-01-2011 Through 25-01-2011",

}

Choudhury, D, Ramsay, WT, Brown, G, Psaila, ND, Beecher, S, Thomson, RR, Kiss, R, Pells, S, Willoughby, NA , Paterson, L & Kar, AK 2011, A femtosecond laser inscribed biochip for stem cell therapeutic applications. in H Becker & BL Gray (eds), Microfluidics, BioMEMS, and Medical Microsystems IX. vol. 7929, SPIE, BELLINGHAM, pp. -, Conference on Microfluidics, BioMEMS, and Medical Microsystems IX, San Francisco, 23/01/11. https://doi.org/10.1117/12.874954

TY - GEN

T1 - A femtosecond laser inscribed biochip for stem cell therapeutic applications

AU - Choudhury, D.

AU - Ramsay, W. T.

AU - Brown, G.

AU - Psaila, N. D.

AU - Beecher, S.

AU - Thomson, R. R.

AU - Kiss, R.

AU - Pells, S.

AU - Willoughby, N. A.

AU - Paterson, L.

AU - Kar, A. K.

PY - 2011

Y1 - 2011

N2 - A continuous flow microfluidic cell separation platform has been designed and fabricated using femtosecond laser inscription. The device is a scalable and non-invasive cell separation mechanism aimed at separating human embryonic stem cells from differentiated cells based on the dissimilarities in their cytoskeletal elasticity. Successful demonstration of the device has been achieved using human leukemia cells the elasticity of which is similar to that of human embryonic stem cells. © 2011 Copyright Society of Photo-Optical Instrumentation Engineers (SPIE).

AB - A continuous flow microfluidic cell separation platform has been designed and fabricated using femtosecond laser inscription. The device is a scalable and non-invasive cell separation mechanism aimed at separating human embryonic stem cells from differentiated cells based on the dissimilarities in their cytoskeletal elasticity. Successful demonstration of the device has been achieved using human leukemia cells the elasticity of which is similar to that of human embryonic stem cells. © 2011 Copyright Society of Photo-Optical Instrumentation Engineers (SPIE).

KW - cell separation

KW - cell sorting

KW - chemical etching

KW - femtosecond laser inscription

KW - fused silica

KW - human embryonic stem cells

UR - http://www.scopus.com/inward/record.url?scp=79957991162&partnerID=8YFLogxK

U2 - 10.1117/12.874954

DO - 10.1117/12.874954

M3 - Conference contribution

SN - 9780819484666

VL - 7929

SP - -

BT - Microfluidics, BioMEMS, and Medical Microsystems IX

A2 - Becker, H

A2 - Gray, BL

PB - SPIE

CY - BELLINGHAM

T2 - Conference on Microfluidics, BioMEMS, and Medical Microsystems IX

Y2 - 23 January 2011 through 25 January 2011

ER -

A femtosecond laser inscribed biochip for stem cell therapeutic applications

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Keywords

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