A concise efficient route to fumitromorgins

Patrick D. Bailey, Philip J. Cochrane, Katrin Lorenz, Ian D. Collier, D. P J Pearson, Georgina M. Rosair

Research output: Contribution to journalArticle

Abstract

Using the kinetically controlled Pictet-Spengler reaction, we have developed a three-step, diastereoselective and enantiospecific synthesis of the natural product demethoxy-fumitremorgin C in 21% overall yield. © 2000 Elsevier Science Ltd.

Original languageEnglish
Pages (from-to)113-115
Number of pages3
JournalTetrahedron Letters
Volume42
Issue number1
DOIs
Publication statusPublished - 1 Jan 2001

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Biological Products
tryptoquivaline

Keywords

  • Alkaloids
  • Anti-tumour
  • Indoles
  • Pictet-Spengler

Cite this

Bailey, P. D., Cochrane, P. J., Lorenz, K., Collier, I. D., Pearson, D. P. J., & Rosair, G. M. (2001). A concise efficient route to fumitromorgins. Tetrahedron Letters, 42(1), 113-115. https://doi.org/10.1016/S0040-4039(00)01899-2
Bailey, Patrick D. ; Cochrane, Philip J. ; Lorenz, Katrin ; Collier, Ian D. ; Pearson, D. P J ; Rosair, Georgina M. / A concise efficient route to fumitromorgins. In: Tetrahedron Letters. 2001 ; Vol. 42, No. 1. pp. 113-115.
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Bailey, PD, Cochrane, PJ, Lorenz, K, Collier, ID, Pearson, DPJ & Rosair, GM 2001, 'A concise efficient route to fumitromorgins', Tetrahedron Letters, vol. 42, no. 1, pp. 113-115. https://doi.org/10.1016/S0040-4039(00)01899-2

A concise efficient route to fumitromorgins. / Bailey, Patrick D.; Cochrane, Philip J.; Lorenz, Katrin; Collier, Ian D.; Pearson, D. P J; Rosair, Georgina M.

In: Tetrahedron Letters, Vol. 42, No. 1, 01.01.2001, p. 113-115.

Research output: Contribution to journalArticle

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T1 - A concise efficient route to fumitromorgins

AU - Bailey, Patrick D.

AU - Cochrane, Philip J.

AU - Lorenz, Katrin

AU - Collier, Ian D.

AU - Pearson, D. P J

AU - Rosair, Georgina M.

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AB - Using the kinetically controlled Pictet-Spengler reaction, we have developed a three-step, diastereoselective and enantiospecific synthesis of the natural product demethoxy-fumitremorgin C in 21% overall yield. © 2000 Elsevier Science Ltd.

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KW - Anti-tumour

KW - Indoles

KW - Pictet-Spengler

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Bailey PD, Cochrane PJ, Lorenz K, Collier ID, Pearson DPJ, Rosair GM. A concise efficient route to fumitromorgins. Tetrahedron Letters. 2001 Jan 1;42(1):113-115. https://doi.org/10.1016/S0040-4039(00)01899-2