A conceptual approach to gene expression analysis enhanced by visual analytics

Cassio Melo, Marie-aude Aufaure, Constantinos Orphanides, Simon Andrews, Kenneth Mcleod, Albert Burger

Research output: Contribution to conferenceOther

Abstract

The analysis of gene expression data is a complex task for biologists wishing to understand the role of genes in the formation of diseases such as cancer. Biologists need greater support when trying to discover, and comprehend, new relationships within their data. In this paper, we describe an approach to the analysis of gene expression data where overlapping groupings are generated by Formal Concept Analysis and interactively analyzed in a tool called CUBIST. The CUBIST workflow involves querying a semantic database and converting the result into a formal context, which can be simplified to make it manageable, before it is visualized as a concept lattice and associated charts.
Original languageEnglish
Pages1314-1319
DOIs
Publication statusPublished - 2013
Eventthe 28th Annual ACM Symposium - Coimbra, Portugal, United Kingdom
Duration: 18 Mar 201322 Mar 2013

Conference

Conferencethe 28th Annual ACM Symposium
CountryUnited Kingdom
CityCoimbra, Portugal
Period18/03/1322/03/13

Fingerprint

Gene expression
Formal concept analysis
Genes
Semantics

Cite this

Melo, C., Aufaure, M., Orphanides, C., Andrews, S., Mcleod, K., & Burger, A. (2013). A conceptual approach to gene expression analysis enhanced by visual analytics. 1314-1319. the 28th Annual ACM Symposium, Coimbra, Portugal, United Kingdom. https://doi.org/10.1145/2480362.2480610
Melo, Cassio ; Aufaure, Marie-aude ; Orphanides, Constantinos ; Andrews, Simon ; Mcleod, Kenneth ; Burger, Albert. / A conceptual approach to gene expression analysis enhanced by visual analytics. the 28th Annual ACM Symposium, Coimbra, Portugal, United Kingdom.
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Melo, C, Aufaure, M, Orphanides, C, Andrews, S, Mcleod, K & Burger, A 2013, 'A conceptual approach to gene expression analysis enhanced by visual analytics' the 28th Annual ACM Symposium, Coimbra, Portugal, United Kingdom, 18/03/13 - 22/03/13, pp. 1314-1319. https://doi.org/10.1145/2480362.2480610

A conceptual approach to gene expression analysis enhanced by visual analytics. / Melo, Cassio; Aufaure, Marie-aude; Orphanides, Constantinos; Andrews, Simon; Mcleod, Kenneth; Burger, Albert.

2013. 1314-1319 the 28th Annual ACM Symposium, Coimbra, Portugal, United Kingdom.

Research output: Contribution to conferenceOther

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Melo C, Aufaure M, Orphanides C, Andrews S, Mcleod K, Burger A. A conceptual approach to gene expression analysis enhanced by visual analytics. 2013. the 28th Annual ACM Symposium, Coimbra, Portugal, United Kingdom. https://doi.org/10.1145/2480362.2480610