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• 2020

  Coherent Control of Light through Laser Written Photonic Lanterns

  Li, S., McNicholl, D. K., Whyte, G., Birks, T. A., Thomson, R. R. & Phillips, D. B., 10 Sep 2020, 2020 Conference on Lasers and Electro-Optics. IEEE, 9192265

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Photonics
  • Imaging techniques
  • Lasers
  • Endoscopy
  • Microfluidics

• Image-Based Single Cell Sorting Automation in Droplet Microfluidics

  Sesen, M. & Whyte, G., 26 May 2020, In: Scientific Reports. 10, 8736.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Microfluidics
  • Sorting
  • Cells
  • Automation
  • Machine learning
  5 Citations (Scopus)

  34 Downloads (Pure)

• Purifying stem cell-derived red blood cells: a high-throughput label-free downstream processing strategy based on microfluidic spiral inertial separation and membrane filtration

  Guzniczak, E., Otto, O., Whyte, G., Chandra, T., Robertson, N. A., Willoughby, N., Jimenez, M. & Bridle, H., Jul 2020, In: Biotechnology and Bioengineering. 117, 7, p. 2032-2045 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Stem cells
  • Microfluidics
  • Cells
  • Blood
  • Labels
  3 Citations (Scopus)

  1 Downloads (Pure)

• Towards Photonic Lantern-Based Microendoscopy

  McNicholl, D., Li, S., Choudhury, D., Repetti, A., Griz-Sanchez, I., Whyte, G., Birks, T. A., Phillips, D. B., Wiaux, Y. & Thomson, R. R., 2020, Conference on Lasers and Electro-Optics/Pacific Rim 2020. Optical Society of America, C10D_5

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Photonics
  • Waveguides
  • photonics
  • waveguides
• 2019

  Assessment of nanomaterial-induced hepatotoxicity using a 3D human primary multi-cellular microtissue exposed repeatedly over 21 days - the suitability of the in vitro system as an in vivo surrogate

  Kermanizadeh, A., Berthing, T., Guzniczak, E., Wheeldon, M., Whyte, G., Vogel, U., Moritz, W. & Stone, V., 19 Nov 2019, In: Particle and Fibre Toxicology. 16, 42.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Nanostructured materials
  • Nanostructures
  • Liver
  • Cytotoxicity
  • In Vitro Techniques
  5 Citations (Scopus)

  12 Downloads (Pure)

• Deformability-induced lift force in spiral microchannels for cell separation

  Guzniczak, E., Otto, O., Whyte, G., Willoughby, N., Jimenez, M. & Bridle, H., 23 Dec 2019, In: Lab on a Chip.

  Research output: Contribution to journal › Article › peer-review

  • Cell Separation
  • Cell Size
  • Microfluidics
  • Biotechnology
  • Point-of-Care Systems
  7 Citations (Scopus)

• Microfluidic devices and systems

  Smith, C. A., Xin, L., Enesa, K., Liu, X., Craig, F. F. & Whyte, G., 2 Apr 2019, Patent No. 10,247,655, 30 Jul 2014

  Research output: Patent

  • microfluidic devices
  • cells
  • oils
  • refractivity
  • classifying
• 2018

  A comparison of methods to assess cell mechanical properties

  Wu, P. H., Aroush, D. R. B., Asnacios, A., Chen, W. C., Dokukin, M. E., Doss, B. L., Durand-Smet, P., Ekpenyong, A., Guck, J., Guz, N. V., Janmey, P. A., Lee, J. S. H., Moore, N. M., Ott, A., Poh, Y. C., Ros, R., Sander, M., Sokolov, I., Staunton, J. R., Wang, N. & 2 others, Whyte, G. & Wirtz, D., 18 Jun 2018, In: Nature Methods. 15, p. 491-498 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cellular Microenvironment
  • Rheology
  • Mechanical Stress
  • Atomic Force Microscopy
  • Elastic Modulus
  130 Citations (Scopus)
• 2015

  A monolithic glass chip for active single-cell sorting based on mechanical phenotyping

  Faigle, C., Lautenschlager, F., Whyte, G., Homewood, P., Martin-Badosa, E. & Guck, J., 7 Mar 2015, In: Lab on a Chip. 15, p. 1267-1275

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Glass
  • Fluorescence
  • Optical Fibers
  • Microfluidics
  • Population
  22 Citations (Scopus)

  389 Downloads (Pure)

• Deformation of phospholipid vesicles in an optical stretcher

  Delabre, U., Feld, K., Crespo, E., Whyte, G., Sykes, C., Seifert, U. & Guck, J., 14 Aug 2015, In: Soft Matter. 11, 30, p. 6075-6088 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Phospholipids
  • traps
  • Heating
  • mechanical properties
  • Elastic constants
  32 Citations (Scopus)

• Microconstriction Arrays for High-Throughput Quantitative Measurements of Cell Mechanical Properties

  Lange, J. R., Steinwachs, J., Kolb, T., Lautscham, L. A., Harder, I., Whyte, G. & Fabry, B., 2015, In: Biophysical Journal. 109, 1, p. 26-34 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Constriction
  • Lab-On-A-Chip Devices
  • Elasticity
  • Suspensions
  • Pressure
  67 Citations (Scopus)

  203 Downloads (Pure)
• 2014

  Dynamically reconfigurable fibre optical spanner

  Kolb, T., Albert, S., Haug, M. & Whyte, G., Feb 2014, In: Lab on a Chip. 14, p. 1186-1190 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Optical Fibers
  • Equipment and Supplies
  • Microfluidics
  • Confocal Microscopy
  15 Citations (Scopus)

  365 Downloads (Pure)

• Dynamic operation of optical fibres beyond the single-mode regime facilitates the orientation of biological cells

  Kreysing, M., Ott, D., Schmidberger, M. J., Otto, O., Schürmann, M., Martín-Badosa, E., Whyte, G. & Guck, J., 2014, In: Nature Communications. 5, 5481.

  Research output: Contribution to journal › Article › peer-review

  • Optical Fibers
  • Optical fibers
  • Optical Tweezers
  • optical fibers
  • Telecommunications
  31 Citations (Scopus)

• Impact of heating on passive and active biomechanics of suspended cells

  Chan, C. J., Whyte, G., Boyde, L., Salbreux, G. & Guck, J., Apr 2014, In: Interface Focus. 4, 2, p. 2013.0069 1 p.

  Research output: Contribution to journal › Article › peer-review

  • Heating
  • Biomechanical Phenomena
  • Temperature
  • TRPV Cation Channels
  • Mechanics
  26 Citations (Scopus)

• Microfluidic systems

  Abell, C., Huck, W. T. S., Bratton, D., Whyte, G. & Fidalgo, L. M., 9 Sep 2014, Patent No. US8828210 B2

  Research output: Patent

  • microfluidic technology
  • droplets
  • emulsions
  • fluids
  • magnetic fields

• Optofluidic rotation of living cells for single-cell tomography

  Kolb, T., Albert, S., Haug, M. & Whyte, G., 2014, In: Journal of Biophotonics.

  Research output: Contribution to journal › Article › peer-review

  • Tomography
  • Flow Cytometry
  • Microfluidics
  • Suspensions
  • Microscopy
  19 Citations (Scopus)

• Separation of blood cells with differing deformability using deterministic lateral displacement

  Holmes, D., Whyte, G., Bailey, J., Vergara-Irigaray, N., Ekpenyong, A., Guck, J. & Duke, T., 2014, In: Interface Focus. 4, 6, 20140011.

  Research output: Contribution to journal › Article › peer-review

  • Blood Cells
  • Equipment and Supplies
  • Leukocytes
  • Hydrodynamics
  • Glutaral
  67 Citations (Scopus)
• 2013

  Elastic theory for the deformation of a solid or layered spheroid under axisymmetric loading

  Boyde, L., Ekpenyong, A., Whyte, G. & Guck, J., Apr 2013, In: Acta Mechanica. 224, 4, p. 819-839 21 p.

  Research output: Contribution to journal › Article › peer-review

  • Poisson ratio
  • Elastic constants
  • Cells
  • Microscopes
  • Elasticity
  6 Citations (Scopus)

• Fashioning microscopic tools

  Phillips, D. B., Whyte, G., Carberry, D. M., Hanna, S., Miles, M. J., Padgett, M. J. & Simpson, S. H., 2013, Optical Trapping and Optical Micromanipulation X. Dholakia, K. & Spalding, G. C. (eds.). Vol. 8810. 881029. (Proceedings of SPIE - The International Society for Optical Engineering; vol. 8810).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Optical tweezers
  • Position measurement
  • field theory (physics)
  • Molding
  • Physics
  3 Citations (Scopus)

• High-resolution imaging of the nuclear envelope for investigation of the mechanical influence of the nucleus on cellular mechanics

  Kolb, T. & Whyte, G., 2013, Optical Molecular Probes, Imaging and Drug Delivery 2013. Optical Society of America, JT2A.33

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • cultured cells
  • Nuclear Envelope
  • Mechanics
  • Nuclear Proteins
  • envelopes

• Rotation of Optically Trapped Living Cells for Single-Cell Tomography

  Kolb, T. & Whyte, G., 2013, Optical Trapping Applications, OTA 2013. p. TM4D.4

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • tomography
  • Tomography
  • Microfluidics
  • cells
  • traps
  1 Citation (Scopus)
• 2012

  Comparison of stresses on homogeneous spheroids in the optical stretcher computed with geometrical optics and generalized Lorenz-Mie theory

  Boyde, L., Ekpenyong, A., Whyte, G. & Guck, J., 20 Nov 2012, In: Applied Optics. 51, 33, p. 7934-7944 11 p.

  Research output: Contribution to journal › Article › peer-review

  • spheroids
  • Mie scattering
  • geometrical optics
  • cells
  • hinges
  18 Citations (Scopus)

• Femtosecond laser fabricated monolithic devices for single cell manipulation

  Bragheri, F., Minzioni, P., Vazquez, R. M., Bellini, N., Paiè, P., Mondello, C., Ramponi, R., Whyte, G., Cristiani, I., Guck, J. & Osellame, R., 2012, Frontiers in Optics 2012. Optical Society of America

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • laser machining
  • classifying
  • manipulators
  • chips
  • fluorescence

• Mechanical environment modulates biological properties of oligodendrocyte progenitor cells.

  Jagielska, A., Norman, A. L., Whyte, G., Van Vliet, K. J., Guck, J., Franklin, R. J. M. & Vliet, K. J. V., Nov 2012, In: Stem Cells and Development. 21, 16, p. 2905-2914 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Oligodendrocyte Precursor Cells
  • Central Nervous System
  • Remyelination
  • Biophysics
  • Polystyrenes
  65 Citations (Scopus)

• Quantitative analysis of deformability-based cell separation using deterministic lateral displacement and optical stretching

  Holmes, D., Whyte, G., Ekpenyong, A., Guck, J. & Duke, T., 2012, Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, p. 536-538 3 p.

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Stretching
  • Formability
  • Stiffness
  • Chemical analysis
  • Shear deformation

• Validation and perspectives of a femtosecond laser fabricated monolithic optical stretcher

  Bellini, N., Bragheri, F., Cristiani, I., Guck, J., Osellame, R. & Whyte, G., 1 Oct 2012, In: Biomedical Optics Express. 3, 10, p. 2658-2668 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Microfluidics
  • Glass
  • Lasers
  • Optical Fibers
  • Single-Cell Analysis
  37 Citations (Scopus)

  60 Downloads (Pure)

• Viscoelastic properties of differentiating blood cells are fate- and function-dependent.

  Ekpenyong, A. E., Whyte, G., Chalut, K., Pagliara, S., Lautenschläger, F., Fiddler, C., Paschke, S., Keyser, U. F., Chilvers, E. R. & Guck, J., Jan 2012, In: PLoS ONE. 7, 9, p. e45237-e45237

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Blood Cells
  • Myeloid Cells
  • Cell Differentiation
  • Physiological Adaptation
  • Differentiation Antigens
  110 Citations (Scopus)

  117 Downloads (Pure)