2-Arylamino-6-ethynylpurines are cysteine-targeting irreversible inhibitors of Nek2 kinase

Christopher J. Matheson, Christopher R. Coxon, Richard Bayliss, Kathy Boxall, Benoit Carbain, Andrew M. Fry, Ian R. Hardcastle, Suzannah J. Harnor, Corine Mas-Droux, David R. Newell, Mark W. Richards, Mangaleswaran Sivaprakasam, David Turner, Roger J. Griffin, Bernard T. Golding, Céline Cano

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Pharmacology, Toxicology and Pharmaceutical Science