α-cycloPNA: 1-Aminocylopentane-1-carboxylic acid-derived peptide nucleic acid

Nicola M. Howarth, L. P G Wakelin, David M. Walker

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

All four diastereoisomers of 3-thymine-1-( tbutoxycarbonyl)aminocyclopentane-1-carboxylic acid have been synthesised from (S)-dimethyl malate and thymine monomer 12 has been incorporated into an a-cycloPNA oligomer.

Original languageEnglish
Pages (from-to)1351-1353
Number of pages3
JournalNucleosides, Nucleotides and Nucleic Acids
Volume22
Issue number5-8
DOIs
Publication statusPublished - 2003

Keywords

  • Cyclic α,α-disubstituted amino acids
  • PNA

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