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Research Output

2020

Characterization of Pot Ale from a Scottish Malt Whisky Distillery and Potential Applications

White, J., Stewart, K., Maskell, D. L., Diallo, A., Traub-Modinger, J. & Willoughby, N., 31 Mar 2020, In : ACS Omega. 5, 12, p. 6429-6440 12 p.

Research output: Contribution to journalArticle

Open Access
File
17 Downloads (Pure)

Integrating micro-algae into wastewater treatment: A review

Mohsenpour, S. F., Hennige, S., Willoughby, N., Adeloye, A. J. & Gutierrez, T., 3 Sep 2020, In : Science of the Total Environment. 752, 142168.

Research output: Contribution to journalReview article

Open Access
File
58 Downloads (Pure)

Pre-fermentation of malt whisky wort using Lactobacillus plantarum and its influence on new-make spirit character

Reid, S., Speers, R. A., Willoughby, N., Lumsden, W. & Maskell, D. L., 1 Aug 2020, In : Food Chemistry. 320, 126605.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Purifying stem cell-derived red blood cells: a high-throughput label-free downstream processing strategy based on microfluidic spiral inertial separation and membrane filtration

Guzniczak, E., Otto, O., Whyte, G., Chandra, T., Robertson, N. A., Willoughby, N., Jimenez, M. & Bridle, H., Jul 2020, In : Biotechnology and Bioengineering. 117, 7, p. 2032-2045 14 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2019

Deformability-induced lift force in spiral microchannels for cell separation

Guzniczak, E., Otto, O., Whyte, G., Willoughby, N., Jimenez, M. & Bridle, H., 23 Dec 2019, In : Lab on a Chip.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2018

Batch anaerobic digestion of deproteinated malt whisky pot ale using different source inocula

Barrena, R., Traub-Modinger, J., Rodriguez Gill, C., Goodwin, J. A. S., Harper, A., Willoughby, N., Sánchez, A. & Aspray, T. J., Jan 2018, In : Waste Management. 71, p. 675-682 8 p.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
378 Downloads (Pure)

Impact of poloxamer 188 (Pluronic F-68) additive on cell mechanical properties, quantification by real-time deformability cytometry

Guzniczak, E., Jimenez, M., Irwin, M., Otto, O., Willoughby, N. & Bridle, H., 22 Aug 2018, In : Biomicrofluidics. 12, 4, 044118.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
10 Downloads (Pure)
2017

Challenges and advances in scale-up of label-free downstream processing for allogeneic cell therapies

Masri, F., Hoeve, M. A., De Sousa, P. A. & Willoughby, N. A., 4 Aug 2017, In : Cell and Gene Therapy Insights. 3, 6, p. 447-467 21 p.

Research output: Contribution to journalReview article

Open Access
File
67 Downloads (Pure)

Effect of organic carbon enrichment on the treatment efficiency of primary settled wastewater by Chlorella vulgaris

Evans, L., Hennige, S. J., Willoughby, N., Adeloye, A., Skroblin, M. & Gutierrez, T., Jun 2017, In : Algal Research. 24, Part A, p. 368–377

Research output: Contribution to journalArticle

Open Access
File
14 Citations (Scopus)
24 Downloads (Pure)

High-throughput assessment of mechanical properties of stem cell derived red blood cells, toward cellular downstream processing

Guzniczak, E., Mohammad Zadeh, M., Dempsey, F., Jimenez, M., Bock, H., Whyte, G., Willoughby, N. & Bridle, H., 31 Oct 2017, In : Scientific Reports. 7, 14457.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
21 Downloads (Pure)

Optically enhanced acoustophoresis

McDougall, C., O'Mahoney, P., McGuinn, A., Willoughby, N. A., Qiu, Y., Demore, C. E. M. & MacDonald, M. P., 25 Aug 2017, Optical Trapping and Optical Micromanipulation XIV. Dholakia, K. & Spalding, G. C. (eds.). SPIE, 103471B. (Proceedings of SPIE; vol. 10347).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2016

A scalable label-free approach to separate human pluripotent cells from differentiated derivatives

Bock, H., Willoughby, N., Hoeve, M., Pells, S., Williams, C., McPhee, G., Freile, P., Choudhury, D. & De Sousa, P., Jan 2016, In : Biomicrofluidics. 10, 16 p., 014107.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
81 Downloads (Pure)

Challenges of Scale-up of Cell Separation and Purification Techniques

Hoeve, M. A., De Sousa, P. A. & Willoughby, N. A., 16 Dec 2016, Bioprocessing for Cell Based Therapies. Connon, C. J. (ed.). Wiley-Blackwell, p. 127-165 39 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Creating an new market opportunity for whisky by-products: challenges and opportunities

Maskell, D. L., White, J., Traub-Modinger, J., Diallo, A., Hughes, P., Harper, A. & Willoughby, N., Mar 2016.

Research output: Contribution to conferencePaper

Effect of CO2 aeration on cultivation of microalgae in luminescent photobioreactors

Mohsenpour, S. F. & Willoughby, N., Feb 2016, In : Biomass and Bioenergy. 85, p. 168-177 10 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Effect of organic carbon enrichment on the treatment efficiency of primary settled wastewater by Chlorella vulgaris

Evans, L., Hennige, S. J., Gutierrez, T., Adeloye, A. & Willoughby, N., 25 Jul 2016, In : New Biotechnology . 33, Supplement, p. S56

Research output: Contribution to journalMeeting abstract

Physicochemical characterisation and batch anaerobic digestion of malt whisky pot ale following a high efficiency deproteination pre-treatment process

Barrena, R., Traub, J. E., Rodriguez Gill, C., Goodwin, J. A. S., Harper, A., Willoughby, N., Sanchez, A. & Aspray, T. J., 14 Nov 2016.

Research output: Contribution to conferencePaper

Protein Recovery

Traub-Modinger, J., White, J., Maskell, D. L., Harper, A., Hughes, P. & Willoughby, N., 7 Jan 2016, IPC No. C07K 1/14 (2006.01), A23K 1/00 (2006.01), C07K 14/81 (2006.01) , Patent No. GB2015/051944, Priority date 3 Jul 2014, Priority No. 1411943.2

Research output: Patent

Recovery and Applications of Proteins from Distillery By-Products

White, J. S., Traub, J. E., Maskell, D. L., Hughes, P. S., Harper, A. J. & Willoughby, N. A., 2016, Protein Byproducts: Transformation from Environmental Burden Into Value-Added Products. Dhillon, G. S. (ed.). Elsevier, p. 235-253 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)
2015

Creating a new market opportunity for whisky by-products

Maskell, D. L., White, J., Traub-Modinger, J., Hughes, P. & Willoughby, N., Sep 2015, Worldwide Distilled Spirits Conference: Future Challenges, New Solutions. Goodall, I., Fotheringham, R., Murray, D., Speers, A. & Walker, G. (eds.). Nottingham, United Kingdom: Context, Vol. 5. p. 367-370 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2014

Development of luminescent photobioreactors for improved microalgae cultivation

Mohsenpour, S. F. & Willoughby, N., Jul 2014, In : New Biotechnology . 31, p. S26-S26 1 p.

Research output: Contribution to journalMeeting abstract

Whisky by-products: a valuable source of protein and potential applications in aquaculture

White, J., Traub, J., Maskell, D., Hughes, P., Harper, A. & Willoughby, N., Jul 2014, In : New Biotechnology . 31, p. S118-S118 1 p.

Research output: Contribution to journalMeeting abstract

2013
58 Citations (Scopus)
2012

A 3D mammalian cell separator biochip

Choudhury, D., Ramsay, W. T., Kiss, R., Willoughby, N. A., Paterson, L. & Kar, A. K., 2012, In : Lab on a Chip. 12, 5, p. 948-953 6 p.

Research output: Contribution to journalArticle

Open Access
File
43 Citations (Scopus)
95 Downloads (Pure)

Industrially Generated Red Blood Cells for Transfusion

Willoughby, N., Dempsey, F. & Mountford, J., 2012.

Research output: Contribution to conferencePaper

Spectral conversion of light for enhanced microalgae growth rates and photosynthetic pigment production

Mohsenpour, S. F., Richards, B. & Willoughby, N., 2012, In : Bioresource Technology. 125, -, p. 75–81

Research output: Contribution to journalArticle

72 Citations (Scopus)
2011

A femtosecond laser inscribed biochip for stem cell therapeutic applications

Choudhury, D., Ramsay, W. T., Brown, G., Psaila, N. D., Beecher, S., Thomson, R. R., Kiss, R., Pells, S., Willoughby, N. A., Paterson, L. & Kar, A. K., 2011, Microfluidics, BioMEMS, and Medical Microsystems IX. Becker, H. & Gray, BL. (eds.). BELLINGHAM: SPIE, Vol. 7929. p. - 6 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Elasticity of Human Embryonic Stem Cells as Determined by Atomic Force Microscopy

Kiss, R., Bock, H., Pells, S., Canetta, E., Adya, A. K., Moore, A. J., De Sousa, P. & Willoughby, N. A., Oct 2011, In : Journal of Biomechanical Engineering. 133, 10, p. - 9 p., 101009.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Ultrafast laser inscription: Science today, technology tomorrow

Choudhury, D., Ramsay, W. T., Willoughby, N. A., Paterson, L. & Kar, A. K., 29 Nov 2011, Passive Components and Fiber-based Devices VIII. Pal, B. P. (ed.). Bellingham (Washington State): SPIE, 11 p. (Passive Components and Fiber-based Devices; vol. 8).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2010

Sorting stem cells using a femtosecond laser inscribed biochip

Choudhury, D., Ramsay, W. T., Psaila, N. D., Brown, G., Beecher, S., Paterson, L., Kar, A. K., Kiss, R., Willoughby, N. A. & Pell, S., 2010, 2010 23RD ANNUAL MEETING OF THE IEEE PHOTONICS SOCIETY. NEW YORK: IEEE, p. 216-217 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)
2009
4 Citations (Scopus)
2008

Large-scale plasmid DNA processing: Evidence that cell harvesting and storage methods affect yield of supercoiled plasmid DNA

Kong, S., Rock, C. F., Booth, A., Willoughby, N., O'Kennedy, R. D., Relton, J., Ward, J. M., Hoare, M. & Levy, M. S., Sep 2008, In : Biotechnology and Applied Biochemistry. 51, 1, p. 43-51 9 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Rhythm of the seers

Willoughby, N., 24 May 2008, In : New Scientist. 198, 2657, p. 21-

Research output: Contribution to journalLetter

2007

Adapted ultra scale-down approach for predicting the centrifugal separation behavior of high cell density cultures

Tustian, A. D., Salte, H., Willoughby, N. A., Hassan, I., Rose, M. H., Baganz, F., Hoare, M. & Titchener-Hooker, N. J., Nov 2007, In : Biotechnology Progress. 23, 6, p. 1404-1410 7 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)
2006
4 Citations (Scopus)
2005

Determining particle density distribution of expanded bed adsorbents

Hassan, S., Titchener-Hooker, N. & Willoughby, N., 5 Dec 2005, In : Biotechnology and Bioengineering. 92, 5, p. 659-663 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2004

Extreme scale-down of expanded bed adsorption: Purification of an antibody fragment directly from recombinant E. coli culture

Willoughby, N., Martin, P. & Titchener-Hooker, N., 5 Sep 2004, In : Biotechnology and Bioengineering. 87, 5, p. 641-647 7 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Use of dimensionless residence time to study variations in breakthrough behaviour in expanded beds formed from varied particle size distributions

Gardner, P. J., Willoughby, N., Hjorth, R., Lacki, K. & Titchener-Hooker, N. J., 5 Aug 2004, In : Biotechnology and Bioengineering. 87, 3, p. 347-353 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2000

Experimental measurement of particle size distribution and voidage in an expanded bed adsorption system

Willoughby, N. A., Hjorth, R. & Titchener-Hooker, N. J., 20 Sep 2000, In : Biotechnology and Bioengineering. 69, 6, p. 648-653 6 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)
11 Citations (Scopus)
1999

Immobilised metal ion affinity chromatography purification of alcohol dehydrogenase from baker's yeast using an expanded bed adsorption system

Willoughby, N. A., Kirschner, T., Smith, M. P., Hjorth, R. & Titchener-Hooker, N. J., 30 Apr 1999, In : Journal of Chromatography A. 840, 2, p. 195-204 10 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)