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Research Output 2010 2019

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Article
2019
Substitution reactions
Temperature
Decomposition
1,3,4-oxadiazole
Pharmaceutical Chemistry

Lithiation Substitution of Unprotected Benzyltetrazoles

Wong, J. Y. F., Lewandowska, A., Trowse, B. & Barker, G., 26 Aug 2019, In : Organic Letters.

Research output: Contribution to journalArticle

Tetrazoles
Substitution reactions
Pharmaceutical Preparations
2017

Metalation-Substitution of an α-Oxygenated Chrial Nitrile

Alshawish, M., Barker, G., Measom, N. D. & Coldham, I., Jun 2017, In : Comptes Rendus Chimie. 20, 6, p. 601-608 8 p.

Research output: Contribution to journalArticle

Open Access
File
nitriles
substitutes
products
2015
Open Access
File
Gold
Alcohols
Ethers
Ether
Protons

Dehydrative Thiolation of Allenols: Indium vs Gold Catalysis

Webster, S., Young, P. C., Barker, G., Rosair, G. M. & Lee, A-L., 2015, In : Journal of Organic Chemistry. 80, p. 1703-1708

Research output: Contribution to journalArticle

Open Access
File
Indium
Catalysis
Sulfhydryl Compounds
Gold

Gold-Catalyzed Proto- and Deuterodeboronation

Barker, G., Webster, S., Johnson, D. G., Curley, R., Andrews, M., Young, P. C., Macgregor, S. A. & Lee, A-L., 16 Oct 2015, In : Journal of Organic Chemistry. 80, 20, p. 9807-9816 10 p.

Research output: Contribution to journalArticle

Open Access
File
Gold
Functional groups
Acids
Boronic Acids
Boron

Indium Versus Gold Catalysis in Dehydrative Reactions with Allylic Alcohols

Webster, S., Schaefer, L., Barker, G. & Lee, A-L., 2 Oct 2015, In : SYNLETT. 26, 19, p. 2673-2678 6 p.

Research output: Contribution to journalArticle

Open Access
File
Indium
Gold
Catalysis
Catalysts
Alkynes
2014

Formation of Unexpected Heterocyclic Products from Pyrolysis of Thiocarbonyl Stabilised Phosphonium Ylides

Aitken, R. A., Barker, G., Cleghorn, L. P., Reid, E. J. & Roberts, S. S., 2014, In : Heterocycles. 88, 2, p. 1135-1147

Research output: Contribution to journalArticle

Pyrolysis
Thiones
Phenylalanine
Alanine
Phosphorus

Gold(I)-Catalysed Direct Thioetherifications Using Allylic Alcohols: an Experimental and Computational Study

Herkert, L., Green, S. L. J., Barker, G., Johnson, D. G., Young, P. C., Macgregor, S. A. & Lee, A., 1 Sep 2014, In : Chemistry - A European Journal. 20, 36, p. 11540-11548

Research output: Contribution to journalArticle

Open Access
File
2013

Asymmetric Lithiation Trapping of N-Boc Heterocycles at Temperatures above −78 °C

Gelardi, G., Barker, G., O'Brien, P. & Blakemore, D. C., 1 Nov 2013, In : Organic Letters. 15, 21, p. 5424-5427 4 p.

Research output: Contribution to journalArticle

Sparteine
Diamines
Temperature

Gold(I)-catalysed one-pot synthesis of chromans using allylic alcohols and phenols

Coutant, E., Young, P. C., Barker, G. & Lee, A-L., 4 Sep 2013, In : Beilstein Journal of Organic Chemistry. 9, p. 1797-1806 10 p.

Research output: Contribution to journalArticle

Open Access
File

Remarkable Configurational Stability of Magnesiated Nitriles

Barker, G., Alshawish, M. R., Skilbeck, M. C. & Coldham, I., 22 Jul 2013, In : Angewandte Chemie International Edition. 52, 30, p. 7700-7703

Research output: Contribution to journalArticle

Nitriles
Deprotonation
Temperature
2012

An Experimental and in Situ IR Spectroscopic Study of the Lithiation–Substitution of N-Boc-2-phenylpyrrolidine and -piperidine: Controlling the Formation of Quaternary Stereocenters

Sheikh, N. S., Leonori, D., Barker, G., Firth, J. D., Campos, K. R., Meijer, A. J. H. M., O'Brien, P. & Coldham, I., 21 Mar 2012, In : Journal of the American Chemical Society. 134, 11, p. 5300-5308 9 p.

Research output: Contribution to journalArticle

Substitution reactions
Piperidines
Monitoring
Nuclear magnetic resonance spectroscopy
Density functional theory
2011

Enantioselective, Palladium-Catalyzed α-Arylation of N-Boc Pyrrolidine: In Situ React IR Spectroscopic Monitoring, Scope, and Synthetic Applications

Barker, G., McGrath, J. L., Klapars, A., Stead, D., Zhou, G., Campos, K. R. & O'Brien, P., 5 Aug 2011, In : Journal of Organic Chemistry. 76, 15, p. 5936-5953

Research output: Contribution to journalArticle

Sparteine
Palladium
Bromides
Monitoring
Deprotonation

Investigation of Bispidines as the Stoichiometric Ligand in the Two-Ligand Catalytic Asymmetric Deprotonation of N-Boc Pyrrolidine

Barker, G., O'Brien, P. & Campos, K. R., 2011, In : Arkivoc. 2011, 5, p. 217-229

Research output: Contribution to journalArticle

Deprotonation
Ligands
N-Boc-pyrrolidine
bispidine
2010

Asymmetric synthesis via aziridinium ions: exploring the stereospecificity of the ring opening of aziridinium ions and a formal synthesis of (−)-swainsonine

Oxenford, S. J., Moore, S., Carbone, G., Barker, G., O'Brien, P., Shipton, M. R., Gilday, J. & Campos, K. R., 23 Jun 2010, In : Tetrahedron: Asymmetry. 21, 11-12, p. 1563-1568 6 p.

Research output: Contribution to journalArticle

Swainsonine
Ions
Diamines
Alcohols

Diamine-Free Lithiation−Trapping of N-Boc Heterocycles using s-BuLi in THF

Barker, G., O'Brien, P. & Campos, K. R., 17 Sep 2010, In : Organic Letters. 12, 18, p. 4176-4179 4 p.

Research output: Contribution to journalArticle

Piperazines
Imidazolidines
Pyrrolidines
Diamines