If you made any changes in Pure these will be visible here soon.

Fingerprint Dive into the research topics where Graeme Barker is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Sparteine Medicine & Life Sciences
Cyclic Nucleotides Medicine & Life Sciences
Gold Medicine & Life Sciences
Diamines Medicine & Life Sciences
Adenosine Monophosphate Medicine & Life Sciences
Cardiovascular Diseases Medicine & Life Sciences
Tetrazoles Medicine & Life Sciences
Piperazines Medicine & Life Sciences

Co Author Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2010 2019

Batch Versus Flow Lithiation-Substitution of 1,3,4-Oxadiazoles: Exploitation of Unstable Intermediates Using Flow Chemistry

Wong, J. Y. F., Tobin, J. M., Vilela, F. & Barker, G., 20 Sep 2019, In : Chemistry - A European Journal. 25, 53, p. 12439-12445 7 p.

Research output: Contribution to journalArticle

Substitution reactions
Temperature
Decomposition
1,3,4-oxadiazole
Pharmaceutical Chemistry

Identification of A Novel Class of Benzofuran Oxoacetic Acid-Derived Ligands that Selectively Activate Cellular EPAC1

Beck, E. M., Parnell, E., Cowley, A., Porter, A., Gillespie, J., Robinson, J., Robinson, L., Pannifer, A. D., Hamon, V., Jones, P., Morrison, A., McElroy, S., Timmerman, M., Rutjes, H., Mahajan, P., Wiejak, J., Luchowska-Stańska, U., Morgan, D., Barker, G., Rehmann, H. & 1 others, Yarwood, S. J., 12 Nov 2019, In : Cells. 8, 11, 1425.

Research output: Contribution to journalArticle

Open Access
File
GTP Phosphohydrolases
Cyclic Nucleotides
Nucleotides
High-Throughput Screening Assays
Ligands

Lithiation Substitution of Unprotected Benzyltetrazoles

Wong, J. Y. F., Lewandowska, A., Trowse, B. & Barker, G., 6 Sep 2019, In : Organic Letters. 21, 17, p. 7069-7072 4 p.

Research output: Contribution to journalArticle

Tetrazoles
Pharmaceutical Chemistry
Pharmaceutical Preparations

Selective small-molecule EPAC activators

Luchowska-Stańska, U., Morgan, D., Yarwood, S. J. & Barker, G., 11 Oct 2019, In : Biochemical Society Transactions. 47, 5, p. 1415-1427 13 p.

Research output: Contribution to journalArticle

Open Access
File
Cyclic Nucleotides
Adenosine Monophosphate
Cyclic AMP-Dependent Protein Kinases
Vascular Resistance
Cyclic AMP

Metalation-Substitution of an α-Oxygenated Chrial Nitrile

Alshawish, M., Barker, G., Measom, N. D. & Coldham, I., Jun 2017, In : Comptes Rendus Chimie. 20, 6, p. 601-608 8 p.

Research output: Contribution to journalArticle

Open Access
File
nitriles
substitutes
products

Activities 2010 2019

P-Stereogenic FLPs

Graeme Barker (Speaker)
13 Sep 2019

Activity: Talk or presentationOral presentation

Lakeland Heterocyclic Symposium

Graeme Barker (Speaker)
11 May 2019

Activity: Talk or presentationOral presentation

RSC Organic Division Scotland Meeting

Graeme Barker (Speaker)
17 Dec 2018

Activity: Talk or presentationOral presentation

ChemCareers 2017 Webinar

Graeme Barker (Speaker)
16 Aug 2017

Activity: Talk or presentationPublic lecture

External Examination for PhD Viva

Graeme Barker (Examiner)
28 Nov 2017

Activity: ExaminationExternal Examiner