Personal profile

Research interests

My principal research interests are in the field of polymeric biomaterials. My current focus is on combining newly developed hydrogels, scaffold materials and cells with biofabrication technologies to prepare 3D tissue constructs for regenerative medicine or to be used as in vitro models. Other research activities include the study of delivery devices for drugs and vaccines. My future aim is to continue advancing biomaterials-based technology platforms for tissue engineering and drug delivery purposes.

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Tissue Engineering Medicine & Life Sciences
Hydrogels Medicine & Life Sciences
Tissue Scaffolds Medicine & Life Sciences
Stereolithography Engineering & Materials Science
Tissue engineering Engineering & Materials Science
Scaffolds (biology) Engineering & Materials Science
Scaffolds Engineering & Materials Science
Hydrogel Medicine & Life Sciences

Co Author Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2006 2018

Comparing Hydrogels for Human Nucleus Pulposus Regeneration: Role of Osmolarity During Expansion

Krouwels, A., Melchels, F. P. W., van Rijen, M. H. P., Öner, F. C., Dhert, W. J. A., Tryfonidou, M. A. & Creemers, L. B. 1 Apr 2018 In : Tissue Engineering Part C: Methods. 24, 4, p. 222-232 11 p.

Research output: Contribution to journalArticle

Hydrogels
Osmolar Concentration
Regeneration
Collagen Type II
Sepharose

Focal adhesion signaling affects regeneration by human nucleus pulposus cells in collagen - but not carbohydrate-based hydrogels

Krouwels, A., Melchels, F. P. W., Van Rijen, M. H. P., ten Brink, C. B. M., Dhert, W. J. A., Öner, F. C., Tryfonidou, M. A. & Creemers, L. B. 15 Jan 2018 In : Acta Biomaterialia. 66, p. 238-247 10 p.

Research output: Contribution to journalArticle

Hydrogels
Focal Adhesions
Regeneration
Collagen
Carbohydrates

3D bioprinting of methacrylated hyaluronic acid (MeHA) hydrogel with intrinsic osteogenicity

Poldervaart, M. T., Goversen, B., De Ruijter, M., Abbadessa, A., Melchels, F., Öner, F. C., Dhert, W. J. A., Vermonden, T. & Alblas, J. 6 Jun 2017 In : PLOS ONE. 12, 6, e0177628

Research output: Contribution to journalArticle

Open Access
File
Bioprinting
Hydrogels
Hydrogel
Hyaluronic Acid
Gels

Biofabrication in Tissue Engineering

Woodfield, T., Lim, K., Morouço, P., Levato, R., Malda, J. & Melchels, F. 2017 Reference Module in Materials Science and Materials Engineering. Elsevier

Research output: Chapter in Book/Report/Conference proceedingOther chapter contribution

Tissue Engineering
Bioprinting
Organoids
Biomedical Engineering
Technology

Improved bovine embryo production in an oviduct-on-a-chip system: prevention of poly-spermic fertilization and parthenogenic activation

Ferraz, M. A. M. M., Henning, H. H. W., Costa, P. F., Malda, J., Melchels, F., Wubbolts, R., Stout, T. A. E., Vos, P. L. A. M. & Gadella, B. M. 7 Mar 2017 In : Lab on a Chip. 17, 5, p. 905-916 12 p.

Research output: Contribution to journalArticle

Open Access
File
fertilization (reproduction)
oviducts
embryo (animal)
cattle
oocytes

Activities 2015 2015

  • 1 Participation in conference

International Conference on Biofabrication

Melchels, F. (Participant)
8 Nov 2015

Activity: Participation in conference