20002020

Research output per year

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Research Output

  • 45 Article
  • 1 Chapter (peer-reviewed)
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2020

Use of EpiAlveolar Lung Model to Predict Fibrotic Potential of Multiwalled Carbon Nanotubes

Barosova, H., Maione, A. G., Septiadi, D., Sharma, M., Haeni, L., Balog, S., O'Connell, O., Jackson, G. R., Brown, D., Clippinger, A. J., Hayden, P., Petri-Fink, A., Stone, V. & Rothen-Rutishauser, B., 28 Apr 2020, In : ACS Nano. 14, 4, p. 3941–3956 16 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
5 Downloads (Pure)
2 Citations (Scopus)
Open Access
File
4 Citations (Scopus)
9 Downloads (Pure)
Open Access
File
4 Citations (Scopus)
3 Downloads (Pure)

The mechanism-based toxicity screening of particles with use in the food and nutrition sector via the ToxTracker reporter system

Brown, D. M., Danielsen, P. H., Derr, R., Moelijker, N., Fowler, P., Stone, V., Hendriks, G., Møller, P. & Kermanizadeh, A., Dec 2019, In : Toxicology in Vitro. 61, 104594.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
1 Downloads (Pure)
Open Access
File
1 Citation (Scopus)
4 Downloads (Pure)
5 Citations (Scopus)
51 Downloads (Pure)
2018

A cross-species and model comparison of the acute toxicity of nanoparticles used in the pigment and ink industries

Brown, D. M., Johnston, H. J., Gaiser, B. K., Pinna, N., Caputo, G., Culha, M., Kelestemur, S., Altunbek, M., Stone, V., Roy, J. C., Kinross, J. H. & Fernandes, T. F., Jul 2018, In : NanoImpact. 11, p. 20–32 13 p.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
52 Downloads (Pure)
Open Access
File
14 Citations (Scopus)
169 Downloads (Pure)

A Flow Cytometry-based Method for the Screening of Nanomaterial-induced Reactive Oxygen Species Production in Leukocytes Subpopulations in Whole Blood

Kermanizadeh, A., Jantzen, K., Brown, D. M., Møller, P. & Loft, S., 1 Jan 2018, In : Basic and Clinical Pharmacology and Toxicology. 122, 1, p. 149–156 8 p.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Assessing the bioactivity of crystalline silica in heated high-temperature insulation wools

Boyles, M., Brown, D. M., Knox, J., Horobin, M., Miller, M. R., Johnston, H. J. & Stone, V., 17 Oct 2018, In : Inhalation Toxicology.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
41 Downloads (Pure)

Corrigendum to "the role of intracellular redox imbalance in nanomaterial induced cellular damage and genotoxicity: A review"

Kermanizadeh, A., Chauché, C., Brown, D. M., Loft, S. & Møller, P., Apr 2018, In : Environmental and Molecular Mutagenesis. 59, 3, p. 263-263 1 p.

Research output: Contribution to journalArticle

Transcriptional profiling reveals gene expression changes associated with inflammation and cell proliferation following short-term inhalation exposure to copper oxide nanoparticles

Costa, P. M., Gosens, I., Williams, A., Farcal, L., Pantano, D., Brown, D. M., Stone, V., Cassee, F. R., Halappanavar, S. & Fadeel, B., Mar 2018, In : Journal of Applied Toxicology. 38, 3, p. 385-397 13 p.

Research output: Contribution to journalArticle

Open Access
File
18 Citations (Scopus)
21 Downloads (Pure)
2017
Open Access
File
22 Citations (Scopus)
116 Downloads (Pure)

Releases from transparent blue automobile coatings containing nanoscale copper phthalocyanine and their effects on J774 A1 macrophages

Pang, C., Neubauer, N., Boyles, M., Brown, D. M., Kanase, N., Hristozov, D., Fernandes, T., Stone, V., Wohlleben, W. & Marcomini, A., Jul 2017, In : NanoImpact. 7, p. 75-83 9 p.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
47 Downloads (Pure)

Surfactants from Itaconic Acid: Toxicity to HaCaT keratinocytes in vitro, Micellar Solubilization, and Skin Permeation Enhancement of Hydrocortisone

Abruzzo, A., Armenise, N., Bigucci, F., Cerchiara, T., Gösser, M. B., Samori, C., Galletti, P., Tagliavini, E., Brown, D. M., Johnston, H. J., Fernandes, T. F. & Luppi, B., 30 May 2017, In : International Journal of Pharmaceutics. 524, 1-2, p. 9–15 7 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
68 Downloads (Pure)

The effect of aluminium and sodium impurities on the in vitro toxicity and pro-inflammatory potential of cristobalite

Nattrass, C., Horwell, C. J., Damby, D. E., Brown, D. M. & Stone, V., Nov 2017, In : Environmental Research. 159, p. 164-175 12 p.

Research output: Contribution to journalArticle

Open Access
File
12 Citations (Scopus)
33 Downloads (Pure)
2016

Inflammatory responses of a human keratinocyte cell line to 10 nm citrate- and PEG-coated silver nanoparticles

Bastos, V., Brown, D. M., Johnston, H. J., Daniel-da-Silva, A. L., Duarte, I. F., Santos, C. & Oliveira, H., 20 Jul 2016, In : Journal of Nanoparticle Research. 18, 205.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
22 Downloads (Pure)

Organ burden and pulmonary toxicity of nano-sized copper (II) oxide particles after short-term inhalation exposure

Gosens, I., Cassee, F. R., Zanella, M., Manodori, L., Brunelli, A., Costa, A. L., Bokkers, B. G. H., De Jong, W. H., Brown, D. M., Hristozov, D. & Stone, V., 2016, In : Nanotoxicology. 10, 8, p. 1084-1095 12 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)

The influence of Citrate or PEG coating on silver nanoparticle toxicity to a human keratinocyte cell line

Bastos, V., Ferreira de Oliveira, J. M. P., Brown, D. M., Johnston, H. J., Malheiro, E., Daniel-da-Silva, A. L., Duarte, I. F., Santos, C. & Oliveira, H., 13 May 2016, In : Toxicology Letters. 249, p. 29-41 13 p.

Research output: Contribution to journalArticle

Open Access
File
37 Citations (Scopus)
47 Downloads (Pure)
2015
4 Citations (Scopus)

Mechanism of neutrophil activation and toxicity elicited by engineered nanomaterials

Johnston, H. J., Brown, D. M., Kanase, N., Euston, M., Gaiser, B. K., Robb, C. T., Dyrynda, E., Rossi, A. G., Brown, E. R. & Stone, V., Aug 2015, In : Toxicology in Vitro. 29, 5, p. 1172-1184 13 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Multi-walled carbon nanotube induced frustrated phagocytosis, cytotoxicity and pro-inflammatory conditions in macrophages are length dependent and greater than that of asbestos

Boyles, M. S. P., Young, L., Brown, D. M., MacCalman, L., Cowie, H., Moisala, A., Smail, F., Smith, P. J. W., Proudfoot, L., Windle, A. H. & Stone, V., Oct 2015, In : Toxicology in Vitro. 29, 7, p. 1513-1528 16 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)

Silica nanoparticles and biological dispersants: genotoxic effects on A549 lung epithelial cells

Brown, D. M., Varet, J., Johnston, H., Chrystie, A. & Stone, V., Oct 2015, In : Journal of Nanoparticle Research. 17, 10, 16 p., 410.

Research output: Contribution to journalArticle

5 Citations (Scopus)

The global variability of diatomaceous earth toxicity: A physicochemical and in vitro investigation

Nattrass, C., Horwell, C. J., Damby, D. E., Kermanizadeh, A., Brown, D. M. & Stone, V., 10 Jul 2015, In : Journal of Occupational Medicine and Toxicology. 10, 23.

Research output: Contribution to journalArticle

Open Access
File
12 Citations (Scopus)
49 Downloads (Pure)

The role of intracellular redox imbalance in nanomaterial induced cellular damage and genotoxicity: a review

Kermanizadeh, A., Chauché, C., Brown, D. M., Loft, S. & Møller, P., Mar 2015, In : Environmental and Molecular Mutagenesis. 56, 2, p. 111-124 14 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
17 Citations (Scopus)
26 Citations (Scopus)
7 Citations (Scopus)

The role of Kupffer cells in the hepatic response to silver nanoparticles

Kermanizadeh, A., Chauché, C., Balharry, D., Brown, D. M., Kanase, N., Boczkowski, J., Lanone, S. & Stone, V., 1 Jan 2014, In : Nanotoxicology. 8, SUPPL. 1, p. 149-154 6 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Toxicological impact of engineered nanomaterials on the liver - a review

Kermanizadeh, A., Gaiser, B. K., Johnston, H., Brown, D. M. & Stone, V., 2014, In : British Journal of Pharmacology.

Research output: Contribution to journalArticle

21 Citations (Scopus)
2013

Effects of alpha-lipoic acid on mtDNA damage after isolated muscle contractions

Fogarty, M. C., Devito, G., Hughes, C. M., Burke, G., Brown, J. C., Mceneny, J., Brown, D. M., McClean, C. & Davison, G. W., Aug 2013, In : Medicine and Science in Sports and Exercise. 45, 8, p. 1469-1477 9 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
11 Citations (Scopus)
2011

Quantum dot cytotoxicity in vitro: an investigation into the cytotoxic effects of a series of different surface chemistries and their core/shell materials

Clift, M. J. D., Varet, J., Hankin, S. M., Brownlee, B., Davidson, A. M., Brandenberger, C., Rothen-Rutishauser, B., Brown, D. M. & Stone, V., Dec 2011, In : Nanotoxicology. 5, 4, p. 664-674 11 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

The uptake and intracellular fate of a series of different surface coated quantum dots in vitro

Clift, M. J. D., Brandenberger, C., Rothen-Rutishauser, B., Brown, D. M. & Stone, V., 8 Jun 2011, In : Toxicology. 286, 1-3, p. 58-68

Research output: Contribution to journalArticle

48 Citations (Scopus)
2010

An investigation into the potential for different surface-coated quantum dots to cause oxidative stress and affect macrophage cell signalling in vitro

Clift, M. J. D., Boyles, M. S. P., Brown, D. M. & Stone, V., Jun 2010, In : Nanotoxicology. 4, 2, p. 139-149 11 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Evaluating the uptake and intracellular fate of polystyrene nanoparticles by primary and hepatocyte cell lines in vitro

Johnston, H. J., Semmler-Behnke, M., Brown, D. M., Kreyling, W., Tran, L. & Stone, V., Jan 2010, In : Toxicology and Applied Pharmacology. 242, 1, p. 66-78 13 p.

Research output: Contribution to journalArticle

115 Citations (Scopus)

Interaction between nanoparticles and cytokine proteins: impact on protein and particle functionality

Brown, D. M., Dickson, C., Duncan, P., Al-Attili, F. & Stone, V., 28 May 2010, In : Nanotechnology. 21, 21, 9 p., 215104.

Research output: Contribution to journalArticle

53 Citations (Scopus)
34 Citations (Scopus)

Relating the physicochemical characteristics and dispersion of multiwalled carbon nanotubes in different suspension media to their oxidative reactivity in vitro and inflammation in vivo

Rothen-Rutishauser, B., Brown, D. M., Piallier-Boyles, M., Kinloch, I. A., Windle, A. H., Gehr, P. & Stone, V., 2010, In : Nanotoxicology. 4, 3, p. 331-42 12 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

The effects of serum on the toxicity of manufactured nanoparticles

Clift, M. J. D., Bhattacharjee, S., Brown, D. M. & Stone, V., 20 Oct 2010, In : Toxicology Letters. 198, 3, p. 358-365 8 p.

Research output: Contribution to journalArticle

70 Citations (Scopus)
2008

The impact of different nanoparticle surface chemistry and size on uptake and toxicity in a murine macrophage cell line

Clift, M. J. D., Rothen-Rutishauser, B., Brown, D. M., Duffin, R., Donaldson, K., Proudfoot, L., Guy, K. & Stone, V., 1 Nov 2008, In : Toxicology and Applied Pharmacology. 232, 3, p. 418-427 10 p.

Research output: Contribution to journalArticle

268 Citations (Scopus)
2000

Toxic and inflammatory effects of filters frequently used for the collection of airborne particulate matter

Dick, C. A. J., Stone, V., Brown, D. M., Watt, M., Cherrie, J. W., Howarth, S., Seaton, A. & Donaldson, K., 2000, In : Atmospheric Environment. 34, 16, p. 2587-2592 6 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)