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Personal profile

Research interests

David's research interests include: The role of oxidative stress in nanoparticle/cell interactions. The role of calcium as a signalling molecule. The effects of particulate air pollution in the lung.

Biography

David's career began in the early 1970s at the Institute of Occupational Medicine (IOM), at that time run by the National coal Board. The Institute conducted research into the health and diseases of miners exposed to coal dust during their working career. This research led to further studies involving workers exposed to asbestos fibres and into cell based studies where attempts were made to understand the effects of man-made mineral fibres in the lung. David moved to the IOM unit at the City Hospital where this work was continued until the mid 1990s.  He then moved to Napier University in 1995 to study the effects of various nanoparticles in the respiratory system under the directorship of Professor Ken Donaldson. During his time at Napier University, he developed various in vitro models to investigate the cellular effects of nanoparticles exposure in different organ systems in the body. David has recently relocated to Heriot-Watt University where this work is continuing.

Fingerprint Dive into the research topics where David McAllister Brown is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Nanostructures Medicine & Life Sciences
Nanoparticles Medicine & Life Sciences
Toxicity Chemical Compounds
Nanostructured materials Chemical Compounds
Cytotoxicity Chemical Compounds
Carbon Nanotubes Medicine & Life Sciences
Macrophages Chemical Compounds
Oxidative Stress Medicine & Life Sciences

Co Author Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2000 2019

  • 42 Article
  • 1 Chapter (peer-reviewed)
Open Access
File
toxicity
toxicology
monoculture
translocation
trend
Macrophages
Cytotoxicity
Nanocomposites
Packaging
Polymers

The mechanism-based toxicity screening of particles with use in the food and nutrition sector via the ToxTracker reporter system

Brown, D. M., Danielsen, P. H., Derr, R., Moelijker, N., Fowler, P., Stone, V., Hendriks, G., Møller, P. & Kermanizadeh, A., 4 Jul 2019, In : Toxicology in Vitro. 61, 104594.

Research output: Contribution to journalArticle

Nutrition
Toxicity
Assays
Screening
Food