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Research Output

  • 37 Article
  • 4 Conference contribution
  • 1 Chapter (peer-reviewed)
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Article
2018

A 256 x 256, 100-kfps, 61% Fill-Factor SPAD Image Sensor for Time-Resolved Microscopy Applications

Gyongy, I., Calder, N., Davies, A., Dutton, N. A. W., Duncan, R. R., Rickman, C., Dalgarno, P. A. & Henderson, R. K., Feb 2018, In : IEEE Transactions on Electron Devices. 65, 2, p. 547-554 8 p.

Research output: Contribution to journalArticle

Open Access
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39 Citations (Scopus)
622 Downloads (Pure)

Cylindrical microlensing for enhanced collection efficiency of small pixel SPAD arrays in single-molecule localisation microscopy

Gyongy, I., Davies, A., Gallinet, B., Dutton, N. A. W., Duncan, R. R., Rickman, C., Henderson, R. K. & Dalgarno, P. A., 5 Feb 2018, In : Optics Express. 26, 3, p. 2280-2291 12 p.

Research output: Contribution to journalArticle

Open Access
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21 Citations (Scopus)
69 Downloads (Pure)
2017

Navigation through the Plasma Membrane Molecular Landscape Shapes Random Organelle Movement

Dun, A., Lord, G. J., Wilson, R. S., Kavanagh, D., Cialowicz, K., Sugita, S., Park, S., Yang, L., Smyth, A. M., Papadopulos, A., Rickman, C. & Duncan, R. R., 6 Feb 2017, In : Current Biology. 27, 3, p. 408–414 7 p.

Research output: Contribution to journalArticle

Open Access
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3 Citations (Scopus)
64 Downloads (Pure)
2016

Automated single particle detection and tracking for large microscopy datasets

Wilson, R. S., Yang, L., Dun, A., Smyth, A. M., Duncan, R. R., Rickman, C. & Lu, W., 1 May 2016, In : Royal Society Open Science. 3, 5, 160225.

Research output: Contribution to journalArticle

Open Access
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13 Citations (Scopus)
54 Downloads (Pure)

Corrigendum: Translation Microscopy (TRAM) for super-resolution imaging

Qiu, Z., Wilson, R. S., Liu, Y., Dun, A. R., Saleeb, R. S., Liu, D., Rickman, C., Frame, M., Duncan, R. R. & Lu, W., 18 Mar 2016, In : Scientific Reports. 6, p. 22313

Research output: Contribution to journalArticle

Open Access
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10 Downloads (Pure)

Marker-Less Stage Drift Correction in Super-Resolution Microscopy Using the Single-Cluster PHD Filter

Schlangen, I., Franco, J., Houssineau, J., Pitkeathly, E., Clark, D., Smal, I. & Rickman, C., Feb 2016, In : IEEE Journal of Selected Topics in Signal Processing. 10, 1, p. 193-202 10 p.

Research output: Contribution to journalArticle

Open Access
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13 Citations (Scopus)
78 Downloads (Pure)

Smart-aggregation imaging for single molecule localisation with SPAD cameras

Gyongy, I., Davies, A., Dutton, N. A. W., Duncan, R. R., Rickman, C., Henderson, R. K. & Dalgarno, P. A., 23 Nov 2016, In : Scientific Reports. 6, 37349.

Research output: Contribution to journalArticle

Open Access
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17 Citations (Scopus)
41 Downloads (Pure)

Translation Microscopy (TRAM) for super-resolution imaging

Qiu, Z., Wilson, R. S., Liu, Y., Dun, A., Saleeb, R. S., Liu, D., Rickman, C., Frame, M., Duncan, R. & Lu, W., 29 Jan 2016, In : Scientific Reports. 6, 19993.

Research output: Contribution to journalArticle

Open Access
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2 Citations (Scopus)
28 Downloads (Pure)
2015

Visualization of the Serratia Type VI Secretion System Reveals Unprovoked Attacks and Dynamic Assembly

Gerc, A., Diepold, A., Trunk, K., Porter, M., Rickman, C., Armitage, J., Stanley-Wall, N. & Coulthurst, S., 29 Sep 2015, In : Cell Reports. 12, 12, p. 2131-2142 12 p.

Research output: Contribution to journalArticle

Open Access
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36 Citations (Scopus)
63 Downloads (Pure)
2014

A molecular toggle after exocytosis sequesters the presynaptic syntaxin1a molecules involved in prior vesicle fusion

Kavanagh, D., Smyth, A. M., Martin, K. J., Dun, A., Brown, E. R., Gordon, S., Smillie, K. J., Chamberlain, L. H., Wilson, R. S., Yang, L., Lu, W., Cousin, M. A., Rickman, C. & Duncan, R. R., 2014, In : Nature Communications. 5, 5774.

Research output: Contribution to journalArticle

Open Access
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13 Citations (Scopus)
89 Downloads (Pure)
2013

Exocytosis through the Lens

Graczyk, A. & Rickman, C., 2013, In : Frontiers in Endocrinology. 4, p. 147

Research output: Contribution to journalArticle

Flashing a light on the spatial organization of transcription

Rickman, C. & Bickmore, W. A., 9 Aug 2013, In : Science. 341, 6146, p. 621-622 2 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Kindlin-1 regulates mitotic spindle formation by interacting with integrins and Plk-1

Patel, H., Zich, J., Serrels, B., Rickman, C., Hardwick, K. G., Frame, M. C. & Brunton, V. G., 27 Jun 2013, In : Nature Communications. 4, n/a, p. 2056

Research output: Contribution to journalArticle

24 Citations (Scopus)

Munc 18-1 Protein Molecules Move between Membrane Molecular Depots Distinct from Vesicle Docking Sites

Smyth, A. M., Yang, L., Martin, K. J., Hamilton, C., Lu, W., Cousin, M. A., Rickman, C. & Duncan, R. R., 15 Feb 2013, In : Journal of Biological Chemistry. 288, 7, p. 5102-5113 12 p.

Research output: Contribution to journalArticle

Open Access
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10 Citations (Scopus)
155 Downloads (Pure)
2012

Secretory vesicles are preferentially targeted to areas of low molecular SNARE density

Yang, L., Dun, A., Martin, K. J., Qiu, Z., Dunn, A., Lord, G. J., Lu, W., Duncan, R. R. & Rickman, C., 2012, In : PLoS ONE. 7, 11, p. e49514

Research output: Contribution to journalArticle

Open Access
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26 Citations (Scopus)
79 Downloads (Pure)
2010

Munc18/syntaxin interaction kinetics control secretory vesicle dynamics

Rickman, C. & Duncan, R. R., 5 Feb 2010, In : Journal of Biological Chemistry. 285, 6, p. 3965-3972 8 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Munc18-1 and syntaxin1: unraveling the interactions between the dynamic duo

Smyth, A. M., Duncan, R. R. & Rickman, C., 2010, In : Cellular and Molecular Neurobiology. 30, 8, p. 1309-13 5 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

The t-SNARE complex: a close up

Dun, A., Rickman, C. & Duncan, R. R., Nov 2010, In : Cellular and Molecular Neurobiology. 30, 8, p. 1321-1326 6 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

t-SNARE protein conformations patterned by the lipid microenvironment

Rickman, C., Medine, C. N., Dun, A. R., Moulton, D. J., Mandula, O., Halemani, N. D., Rizzoli, S. O., Chamberlain, L. H. & Duncan, R. R., 30 Apr 2010, In : Journal of Biological Chemistry. 285, 18, p. 13535-13541 7 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Vesicle fusion probability is determined by the specific interactions of munc18

Smyth, A. M., Rickman, C. & Duncan, R. R., 3 Dec 2010, In : Journal of Biological Chemistry. 285, 49, p. 38141-38148 8 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2009

Inhibiting pro-death NMDA receptor signaling dependent on the NR2 PDZ ligand may not affect synaptic function or synaptic NMDA receptor signaling to gene expression

Martel, M-A., Soriano, F. X., Baxter, P., Rickman, C., Duncan, R., Wyllie, D. J. A. & Hardingham, G. E., 2009, In : Channels. 3, 1, p. 12-15 4 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
2008

Specific targeting of pro-death NMDA receptor signals with differing reliance on the NR2B PDZ ligand

Soriano, F. X., Martel, M-A., Papadia, S., Vaslin, A., Baxter, P., Rickman, C., Forder, J., Tymianski, M., Duncan, R., Aarts, M., Clarke, P., Wyllie, D. J. A. & Hardingham, G. E., 2008, In : Journal of Neuroscience Research. 28, 42, p. 10696-710 15 p.

Research output: Contribution to journalArticle

125 Citations (Scopus)
2007

Functionally and spatially distinct modes of munc18-syntaxin 1 interaction

Rickman, C., Medine, C. N., Bergmann, A. & Duncan, R. R., 20 Apr 2007, In : Journal of Biological Chemistry. 282, 16, p. 12097-12103 7 p.

Research output: Contribution to journalArticle

98 Citations (Scopus)

Mechanism of arachidonic acid action on syntaxin-Munc18

Connell, E., Darios, F., Broersen, K., Gatsby, N., Peak-Chew, S-Y., Rickman, C. & Davletov, B., 2007, In : EMBO Reports. 8, 4, p. 414-9 6 p.

Research output: Contribution to journalArticle

64 Citations (Scopus)

Munc18-1 prevents the formation of ectopic SNARE complexes in living cells

Medine, C. N., Rickman, C., Chamberlain, L. H. & Duncan, R. R., 15 Dec 2007, In : Journal of Cell Science. 120, 24, p. 4407-4415 9 p.

Research output: Contribution to journalArticle

60 Citations (Scopus)
2006

Conserved prefusion protein assembly in regulated exocytosis

Rickman, C., Jiménez, J. L., Graham, M. E., Archer, D. A., Soloviev, M., Burgoyne, R. D. & Davletov, B., 1 Jan 2006, In : Molecular Biology of the Cell. 17, 1, p. 283-294 12 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)
2005

Arachidonic acid allows SNARE complex formation in the presence of Munc18

Rickman, C. & Davletov, B., May 2005, In : Chemistry and Biology. 12, 5, p. 545-553 9 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)

Self-assembly of SNARE fusion proteins into star-shaped oligomers

Rickman, C., Hu, K., Carroll, J. & Davletov, B., 15 May 2005, In : Biochemical Journal. 388, 1, p. 75-79 5 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)
2004

A common mechanism for the regulation of vesicular SNAREs on phospholipid membranes

Hu, K., Rickman, C., Carroll, J. & Davletov, B., 1 Feb 2004, In : Biochemical Journal. 377, 3, p. 781-785 5 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

A molecular basis underlying differences in the toxicity of botulinum serotypes A and E

Bajohrs, M., Rickman, C., Binz, T. & Davletov, B., 2004, In : EMBO Reports. 5, 11, p. 1090-5 6 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Comparative analysis of tandem C2 domains from the mammalian synaptotagmin family

Rickman, C., Craxton, M., Osborne, S. & Davletov, B., 1 Mar 2004, In : Biochemical Journal. 378, 2, p. 681-686 6 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

High affinity interaction of syntaxin and SNAP-25 on the plasma membrane is abolished by botulinum toxin E

Rickman, C., Meunier, F. A., Binz, T. & Davletov, B., 2 Jan 2004, In : Journal of Biological Chemistry. 279, 1, p. 644-651 8 p.

Research output: Contribution to journalArticle

72 Citations (Scopus)

Synaptotagmin interaction with the syntaxin/SNAP-25 dimer is mediated by an evolutionarily conserved motif and is sensitive to inositol hexakisphosphate

Rickman, C., Archer, D. A., Meunier, F. A., Craxton, M., Fukuda, M., Burgoyne, R. D. & Davletov, B., 26 Mar 2004, In : Journal of Biological Chemistry. 279, 13, p. 12574-12579 6 p.

Research output: Contribution to journalArticle

95 Citations (Scopus)
2003

Mechanism of calcium-independent synaptotagmin binding to target SNAREs

Rickman, C. & Davletov, B., 21 Feb 2003, In : Journal of Biological Chemistry. 278, 8, p. 5501-5504 4 p.

Research output: Contribution to journalArticle

75 Citations (Scopus)
2002

Action of complexin on SNARE complex

Hu, K., Carroll, J., Rickman, C. & Davletov, B., 1 Nov 2002, In : Journal of Biological Chemistry. 277, 44, p. 41652-41656 5 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)

Increased actin polymerization reduces the inhibition of serum response factor activity by Yin Yang 1

Ellis, P. D., Martin, K. M., Rickman, C., Metcalfe, J. C. & Kemp, P. R., 1 Jun 2002, In : Biochemical Journal. 364, 2, p. 547-554 8 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Vesicular restriction of synaptobrevin suggests a role for calcium in membrane fusion

Hu, K., Carroll, J., Fedorovich, S., Rickman, C., Sukhodub, A. & Davletov, B., 7 Feb 2002, In : Nature. 415, 6872, p. 646-650 5 p.

Research output: Contribution to journalArticle

155 Citations (Scopus)