Research output per year
Research output per year
Personal profile
Research interests
- Per- and polyfluoroalkyl substances (PFAS)
- Mixture toxicity
- The role of HIF1 in male reproductive health
Biography
Chris's background in toxicology begins after graduaing from the University of Abertay Dundee with a BSc in Biotechnology, working for CXR Biosciences - a specialist toxicology CRO based in Dundee. Over the years, firstly working at CXR, and later Concept Life Sciences, Chris gained many skills and expertise in toxicology, cumulating in becoming a European Registered Toxicologist. After almost a decade in contract research, Chris decided to return to academia, firstly gaining an MSc in Drug Discovery and Development from the University of Aberdeen, and then a PhD in Toxicology from the University of Glasgow. Chris spent a period as a post-doctoral scientist at the Drug Discovery Unit of the University of Dundee before in 2024 joining Heriot-Watt University as an Assistant Professor based in the Institute of Biological Chemistry, Biophysics, and Bioengineering.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Research output
- 7 Article
-
In-utero exposure to real-life environmental chemicals disrupts gene expression within the hypothalamo-pituitary-gonadal axis of prepubertal and adult rams
Ghasemzadeh-Hasankolaei, M., Evans, N. P., Elcombe, C. S., Lea, R. G., Sinclair, K. D., Padmanabhan, V. & Bellingham, M., 1 Jan 2025, In: Environmental Research. 264, Part 1, 120303.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
Preconceptional and in utero exposure of sheep to a real‐life environmental chemical mixture disrupts key markers of energy metabolism in male offspring
Ghasemzadeh‐Hasankolaei, M., Elcombe, C. S., Powls, S., Lea, R. G., Sinclair, K. D., Padmanabhan, V., Evans, N. P. & Bellingham, M., Jan 2024, In: Journal of Neuroendocrinology. 36, 1, e13358.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)14 Downloads (Pure) -
Developmental exposure to a real-life environmental chemical mixture alters testicular transcription factor expression in neonatal and pre-pubertal rams, with morphological changes persisting into adulthood
Elcombe, C. S., Monteiro, A., Ghasemzadeh-Hasankolaei, M., Padmanabhan, V., Lea, R. G., Sinclair, K. D., Evans, N. P. & Bellingham, M., Jun 2023, In: Environmental Toxicology and Pharmacology. 100, 104152.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)12 Downloads (Pure) -
Sexually dimorphic impact of preconceptional and gestational exposure to a real-life environmental chemical mixture (biosolids) on offspring growth dynamics and puberty in sheep
Evans, N. P., Bellingham, M., Elcombe, C. S., Ghasemzadeh-Hasankolaei, M., Lea, R. G., Sinclair, K. D. & Padmanabhan, V., Sept 2023, In: Environmental Toxicology and Pharmacology. 102, 104257.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)12 Downloads (Pure) -
Critical review and analysis of literature on low dose exposure to chemical mixtures in mammalian in vivo systems
Elcombe, C. S., Evans, N. P. & Bellingham, M., 27 Jul 2022, In: Critical Reviews in Toxicology. 52, 3, p. 221-238Research output: Contribution to journal › Article › peer-review
Open Access26 Citations (Scopus)