Description
The course aims to enable students:1. Gain a broad knowledge and understanding of the role of transition metal catalysis, asymmetric synthesis, short-lived intermediates, photo-redox, microwave, and flow chemistry in modern organic synthesis.
2. Propose strategies for the synthesis of unseen target molecules of increased appropriate complexity.
3. Formulate curly arrow mechanisms and catalytic cycles at an advanced level for a range of reactions involving transition metal and photo-redox catalysts, as well as short-lived intermediates.
4. Construct drawings of substrate-preferred conformation and reaction transition states to explain the stereochemical outcome of diastereo- and enantioselective reactions.