Carbon capture and storage (CCS) is the most viable technology that allows the continued use of fossil fuels while addressing the carbon emission problem from anthropogenic activities. For the secure and successful storage of the emitted and damaging CO2, deep saline aquifers are the preferred choice. This is mainly due to their wide geographical spread, as well as large potential storage capacity. Nevertheless, the injection of CO2 into a saline aquifer causes the removal of water by immiscible displacement, as well as evaporation into the CO2-rich phase. This can alter the petrophysical properties of the formation rock due to salt deposition in the pore spaces. The impairment of permeability can cause operational problems, as it leads to pressure build-up during CO2 injection.